PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ERBB4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017862; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022833
Chromosome Location:   2:212652836-212812280question
Amplicon Length:   145

Gene Information

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains a transmembrane domain a tyrosine kinase domain a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however not all variants have been fully characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   ERBB4
Gene Name:   v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Aliases:   HER4, MGC138404, p180erbB4
RefSeq:   NC_000002.11 NT_005403.17 NG_011805.1
Ensembl:   ENSG00000178568
Entrez:   2066
UniGene:   Hs.390729
Chromosome Mapping:   2q33.3-q34

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