PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TAB1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017701; Intron-spanning

List Price:    $134.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022717
Chromosome Location:   22:39822838-39824081question
Amplicon Length:   119

Gene Information

The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1 which is known to mediate various intracellular signaling pathways such as those induced by TGF beta interleukin 1 and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1 while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha) and thus represents an alternative activation pathway in addition to the MAPKK pathways which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   TAB1
Gene Name:   TGF-beta activated kinase 1/MAP3K7 binding protein 1
Aliases:   3'-Tab1, MAP3K7IP1, MGC57664
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000100324
Entrez:   10454
UniGene:   Hs.507681
Chromosome Mapping:   22q13.1

Number Description Download
10033487 ddPCR™ Mutation Detection Assays Product Insert, Ver C Click to download
10033173 ddPCR™ Copy Number Variation Assays Product Insert, Ver C Click to download
10041702 PrimePCR™ ddPCR™ Gene Expression Assays (EvaGreen) Product Insert, Rev A Click to download
10047489 ddPCR™ Mutation Detection Assays Product Insert, Ver B Click to download
10048730 PrimePCR™ ddPCR™ Gene Expression Probe Assays Product Insert, Rev A Click to download