PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ALOXE3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017551; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022603
Chromosome Location:   17:8018971-8020197question
Amplicon Length:   110

Gene Information

This gene is a member of the lipoxygenase family which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R12R-epoxyeicosa-5Z9E14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Sep 2009]

Gene Symbol:   ALOXE3
Gene Name:   arachidonate lipoxygenase 3
Aliases:   E-LOX, MGC119694, MGC119695, MGC119696, eLOX3
RefSeq:   NC_000017.10 NG_015807.1 NT_010718.16
Ensembl:   ENSG00000179148
Entrez:   59344
UniGene:   Hs.232770
Chromosome Mapping:   17p13.1

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