PrimePCR™ ddPCR™ Expression EvaGreen® Assay: LEP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017538; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022593
Chromosome Location:   7:127892170-127894561question
Amplicon Length:   121

Gene Information

This gene encodes a protein that is secreted by white adipocytes and which plays a major role in the regulation of body weight. This protein which acts through the leptin receptor functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions and is involved in the regulation of immune and inflammatory responses hematopoiesis angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq Jul 2008]

Gene Symbol:   LEP
Gene Name:   leptin
Aliases:   FLJ94114, OB, OBS
RefSeq:   NC_000007.13 NG_007450.1 NT_007933.15
Ensembl:   ENSG00000174697
Entrez:   3952
UniGene:   Hs.194236
Chromosome Mapping:   7q31.3

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