This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCID0017484; Intron-spanning
This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide an insulin growth factor binding domain a Kazal protease inhibitor domain a conserved trypsin domain and a PDZ domain. Based on studies on other related family members this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis tumor suppression unfolded stress response apoptosis and aging. [provided by RefSeq Oct 2008]