PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SLC12A3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017314; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022415
Chromosome Location:   16:56916331-56918035question
Amplicon Length:   124

Gene Information

This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome a disease similar to Bartter's syndrome that is characterized by hypokalemic alkalosis combined with hypomagnesemia low urinary calcium and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   SLC12A3
Gene Name:   solute carrier family 12 (sodium/chloride transporters), member 3
Aliases:   FLJ96318, NCCT, TSC
RefSeq:   NC_000016.9 NG_009386.1 NT_010498.15
Ensembl:   ENSG00000070915
Entrez:   6559
UniGene:   Hs.669115
Chromosome Mapping:   16q13

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