PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PLAUR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017227; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022352
Chromosome Location:   19:44160738-44169587question
Amplicon Length:   145

Gene Information

This gene encodes the receptor for urokinase plasminogen activator and given its role in localizing and promoting plasmin formation likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq Jul 2008]

Gene Symbol:   PLAUR
Gene Name:   plasminogen activator, urokinase receptor
Aliases:   CD87, U-PAR, UPAR, URKR
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000011422
Entrez:   5329
UniGene:   Hs.466871
Chromosome Mapping:   19q13

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