PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MYOM1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017164; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022296
Chromosome Location:   18:3187592-3188816question
Amplicon Length:   85

Gene Information

The giant protein titin together with its associated proteins interconnects the major structure of sarcomeres the M bands and Z discs. The C-terminal end of the titin string extends into the M line where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein myomesin 1 like myomesin 2 titin and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   MYOM1
Gene Name:   myomesin 1, 185kDa
Aliases:   MGC134946, MGC134947, SKELEMIN
RefSeq:   NC_000018.9 NT_010859.14
Ensembl:   ENSG00000101605
Entrez:   8736
UniGene:   Hs.464469
Chromosome Mapping:   18p11.31

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