PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RASA1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017106; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022253
Chromosome Location:   5:86645144-86658418question
Amplicon Length:   138

Gene Information

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Alternative splicing results in two isoforms where the shorter isoform lacking the N-terminal hydrophobic region but retaining the same activity appears to be abundantly expressed in placental but not adult tissues. [provided by RefSeq Jul 2008]

Gene Symbol:   RASA1
Gene Name:   RAS p21 protein activator (GTPase activating protein) 1
Aliases:   CM-AVM, CMAVM, DKFZp434N071, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP
RefSeq:   NC_000005.9 NG_011650.1 NT_006713.15
Ensembl:   ENSG00000145715
Entrez:   5921
UniGene:   Hs.664080
Chromosome Mapping:   5q13.3

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