PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CASP14, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017034; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022186
Chromosome Location:   19:15164710-15166014question
Amplicon Length:   76

Gene Information

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits large and small that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation which is important for the formation of the skin barrier. [provided by RefSeq Jul 2008]

Gene Symbol:   CASP14
Gene Name:   caspase 14, apoptosis-related cysteine peptidase
Aliases:   MGC119078, MGC119079
RefSeq:   NC_000019.9 NT_011295.11
Ensembl:   ENSG00000105141
Entrez:   23581
UniGene:   Hs.466057
Chromosome Mapping:   19p13.1

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