PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SAFB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017006; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022161
Chromosome Location:   19:5654379-5657295question
Amplicon Length:   103

Gene Information

This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Jan 2011]

Gene Symbol:   SAFB
Gene Name:   scaffold attachment factor B
Aliases:   DKFZp779C1727, HAP, HET, SAF-B1, SAFB1
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000160633
Entrez:   6294
UniGene:   Hs.728802
Chromosome Mapping:   19p13.3-p13.2

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