PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PKN1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016992; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022147
Chromosome Location:   19:14554343-14557312question
Amplicon Length:   136

Gene Information

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq Jul 2008]

Gene Symbol:   PKN1
Gene Name:   protein kinase N1
Aliases:   DBK, MGC46204, PAK-1, PAK1, PKN, PKN-ALPHA, PRK1, PRKCL1
RefSeq:   NC_000019.9 NT_011295.11
Ensembl:   ENSG00000123143
Entrez:   5585
UniGene:   Hs.466044
Chromosome Mapping:   19p13.12

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