PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CILP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016987; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022142
Chromosome Location:   15:65494326-65496607question
Amplicon Length:   122

Gene Information

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP) which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase however later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq Sep 2010]

Gene Symbol:   CILP
Gene Name:   cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Aliases:   CILP-1, HsT18872
RefSeq:   NC_000015.9 NG_012214.1 NT_010194.17
Ensembl:   ENSG00000138615
Entrez:   8483
UniGene:   Hs.442180
Chromosome Mapping:   15q22

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