PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DCLK2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016846; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5022016
Chromosome Location:   4:151114322-151119220question
Amplicon Length:   108

Gene Information

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains which bind microtubules and regulate microtubule polymerization a C-terminal serine/threonine protein kinase domain which shows substantial homology to Ca2+/calmodulin-dependent protein kinase and a serine/proline-rich domain in between the doublecortin and the protein kinase domains which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene another family member and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq Sep 2010]

Gene Symbol:   DCLK2
Gene Name:   doublecortin-like kinase 2
Aliases:   CL2, CLICK-II, CLICK2, CLIK2, DCAMKL2, DCDC3, DCDC3B, DCK2, DKFZp761I032, MGC45428
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000170390
Entrez:   166614
UniGene:   Hs.591683
Chromosome Mapping:   4q31.3

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