PrimePCR™ ddPCR™ Expression EvaGreen® Assay: APOB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016796; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5021977
Chromosome Location:   2:21251341-21252587question
Amplicon Length:   117

Gene Information

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA) resulting in the creation of a stop codon and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia normotriglyceridemic hypobetalipoproteinemia and hypercholesterolemia due to ligand-defective apoB diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq Jul 2008]

Gene Symbol:   APOB
Gene Name:   apolipoprotein B (including Ag(x) antigen)
Aliases:   FLDB, LDLCQ4
RefSeq:   NC_000002.11 NG_011793.1 NT_022184.15
Ensembl:   ENSG00000084674
Entrez:   338
UniGene:   Hs.120759
Chromosome Mapping:   2p24-p23

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