PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MAP3K5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016590; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5021800
Chromosome Location:   6:136901503-136904805question
Amplicon Length:   125

Gene Information

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK) MAPK kinase (MKK or MEK) and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase MAPK kinase/MEK which in turn activates MAPK. The kinases of these signaling cascades are highly conserved and homologs exist in yeast Drosophila and mammalian cells. MAPKKK5 contains 1374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1 MAPKK4) in vitro and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq Jul 2008]

Gene Symbol:   MAP3K5
Gene Name:   mitogen-activated protein kinase kinase kinase 5
Aliases:   ASK1, MAPKKK5, MEKK5
RefSeq:   NC_000006.11 NG_011965.1 NT_025741.15
Ensembl:   ENSG00000197442
Entrez:   4217
UniGene:   Hs.186486
Chromosome Mapping:   6q22.33

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