PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PLN, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016488; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5021713
Chromosome Location:   6:118869495-118880055question
Amplicon Length:   99

Gene Information

The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq Jul 2008]

Gene Symbol:   PLN
Gene Name:   phospholamban
Aliases:   CMD1P, PLB
RefSeq:   NC_000006.11 NG_009082.1 NG_021248.1 NT_025741.15
Ensembl:   ENSG00000198523
Entrez:   5350
UniGene:   Hs.170839
Chromosome Mapping:   6q22.1

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