PrimePCR™ ddPCR™ Expression EvaGreen® Assay: IL12B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016458; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5021688
Chromosome Location:   5:158745838-158747359question
Amplicon Length:   80

Gene Information

This gene encodes a subunit of interleukin 12 a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS) suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq Jul 2008]

Gene Symbol:   IL12B
Gene Name:   interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
Aliases:   CLMF, CLMF2, IL-12B, NKSF, NKSF2
RefSeq:   NC_000005.9 NG_009618.1 NT_023133.13
Ensembl:   ENSG00000113302
Entrez:   3593
UniGene:   Hs.674
Chromosome Mapping:   5q31.1-q33.1

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