PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GCH1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016358; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5021602
Chromosome Location:   14:55326399-55332129question
Amplicon Length:   111

Gene Information

This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis catalyzing the conversion of GTP into 78-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however not all variants give rise to a functional enzyme. [provided by RefSeq Jul 2008]

Gene Symbol:   GCH1
Gene Name:   GTP cyclohydrolase 1
Aliases:   DYT14, DYT5, DYT5a, GCH, GTP-CH-1, GTPCH1, HPABH4B
RefSeq:   NC_000014.8 NG_008647.1 NT_026437.12
Ensembl:   ENSG00000131979
Entrez:   2643
UniGene:   Hs.86724
Chromosome Mapping:   14q22.1-q22.2

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