PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DNMT3B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0016111; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5021392
Chromosome Location:   20:31375198-31376717question
Amplicon Length:   88

Gene Information

CpG methylation is an epigenetic modification that is important for embryonic development imprinting and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq May 2011]

Gene Symbol:   DNMT3B
Gene Name:   DNA (cytosine-5-)-methyltransferase 3 beta
Aliases:   ICF, M.HsaIIIB
RefSeq:   NC_000020.10 NG_007290.1 NT_011362.10
Ensembl:   ENSG00000088305
Entrez:   1789
UniGene:   Hs.713611
Chromosome Mapping:   20q11.2

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