PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CTCF, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0015701; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5021040
Chromosome Location:   16:67660571-67662374question
Amplicon Length:   120

Gene Information

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element it can block communication between enhancers and upstream promoters thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers prostate cancers and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2010]

Gene Symbol:   CTCF
Gene Name:   CCCTC-binding factor (zinc finger protein)
Aliases:   Not Available
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000102974
Entrez:   10664
UniGene:   Hs.368367
Chromosome Mapping:   16q21-q22.3

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