PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DCC, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0015678; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5021019
Chromosome Location:   18:50731669-50734109question
Amplicon Length:   97

Gene Information

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq Oct 2009]

Gene Symbol:   DCC
Gene Name:   deleted in colorectal carcinoma
Aliases:   CRC18, CRCR1, IGDCC1
RefSeq:   NC_000018.9 NG_013341.1 NT_010966.14
Ensembl:   ENSG00000187323
Entrez:   1630
UniGene:   Hs.162025
Chromosome Mapping:   18q21.3

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