PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MMP2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0015623; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5020967
Chromosome Location:   16:55519623-55522561question
Amplicon Length:   144

Gene Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   MMP2
Gene Name:   matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
Aliases:   CLG4, CLG4A, MMP-II, MONA, TBE-1
RefSeq:   NC_000016.9 NT_010498.15 NG_008989.1
Ensembl:   ENSG00000087245
Entrez:   4313
UniGene:   Hs.513617
Chromosome Mapping:   16q13-q21

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