This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCID0015475; Intron-spanning
The protein encoded by this gene binds to the cytoplasmic tail of CD2 an effector of T cell activation and adhesion negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1 PTPN18 WAS CD2AP and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq Jul 2008]