PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GHR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0015051; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5020505
Chromosome Location:   5:42695109-42700071question
Amplicon Length:   199

Gene Information

This gene encodes a member of the type I cytokine receptor family which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome also known as the growth hormone insensitivity syndrome (GHIS) a disorder characterized by short stature. In humans and rabbits but not rodents growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq Jun 2011]

Gene Symbol:   GHR
Gene Name:   growth hormone receptor
Aliases:   GHBP
RefSeq:   NC_000005.9 NG_011688.1 NT_006576.16
Ensembl:   ENSG00000112964
Entrez:   2690
UniGene:   Hs.125180
Chromosome Mapping:   5p13-p12

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