PrimePCR™ ddPCR™ Expression EvaGreen® Assay: LILRB4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0015016; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5020479
Chromosome Location:   19:55175908-55177339question
Amplicon Length:   172

Gene Information

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains a transmembrane domain and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   LILRB4
Gene Name:   leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
Aliases:   CD85K, HM18, ILT3, LILRB5, LIR-5, LIR5
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000186818
Entrez:   11006
UniGene:   Hs.67846
Chromosome Mapping:   19q13.4

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