PrimePCR™ ddPCR™ Expression EvaGreen® Assay: APEX2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0014167; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019877
Chromosome Location:   X:55026953-55028725question
Amplicon Length:   156

Gene Information

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). [provided by RefSeq Jul 2008]

Gene Symbol:   APEX2
Gene Name:   APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Aliases:   APE2, APEXL2, XTH2
RefSeq:   NC_000023.10 NG_008983.1 NG_012568.1 NT_011630.14
Ensembl:   ENSG00000169188
Entrez:   27301
UniGene:   Hs.659558
Chromosome Mapping:   Xp11.21

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