This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCID0014047; Intron-spanning
The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor also called somatocrinin that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism while hypersecretion of the encoded protein is a cause of gigantism. [provided by RefSeq Jul 2008]