PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NR0B2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0014043; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019778
Chromosome Location:   1:27238397-27239945question
Amplicon Length:   197

Gene Information

The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family a group of transcription factors regulated by small hydrophobic hormones a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors inhibiting their ligand-dependent transcriptional activation. In addition interaction with estrogen receptors has been demonstrated leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq Jul 2008]

Gene Symbol:   NR0B2
Gene Name:   nuclear receptor subfamily 0, group B, member 2
Aliases:   FLJ17090, SHP, SHP1
RefSeq:   NC_000001.10 NG_012143.1 NT_004610.19
Ensembl:   ENSG00000131910
Entrez:   8431
UniGene:   Hs.427055
Chromosome Mapping:   1p36.1

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