PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CCND1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013833; Intron-spanning

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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019626
Chromosome Location:   11:69456176-69457867question
Amplicon Length:   143

Gene Information

The protein encoded by this gene belongs to the highly conserved cyclin family whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6 whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations amplification and overexpression of this gene which alters cell cycle progression are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq Jul 2008]

Gene Symbol:   CCND1
Gene Name:   cyclin D1
Aliases:   BCL1, D11S287E, PRAD1, U21B31
RefSeq:   NC_000011.9 NG_007375.1 NT_167190.1
Ensembl:   ENSG00000110092
Entrez:   595
UniGene:   Hs.523852
Chromosome Mapping:   11q13

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