PrimePCR™ ddPCR™ Expression EvaGreen® Assay: USP2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013654; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019488
Chromosome Location:   11:119228887-119229770question
Amplicon Length:   148

Gene Information

This gene encodes a member of the family of de-ubiquitinating enzymes which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase murine double minute 2 (MDM2) MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2011]

Gene Symbol:   USP2
Gene Name:   ubiquitin specific peptidase 2
Aliases:   UBP41, USP9
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000036672
Entrez:   9099
UniGene:   Hs.524085
Chromosome Mapping:   11q23.3

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