PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PPM1F, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013599; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019447
Chromosome Location:   22:22279970-22285566question
Amplicon Length:   83

Gene Information

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX) and thus block the effects of p21-activated kinase 1 (PAK) a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified but its full-length nature has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   PPM1F
Gene Name:   protein phosphatase, Mg2+/Mn2+ dependent, 1F
Aliases:   CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2, hFEM-2
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000100034
Entrez:   9647
UniGene:   Hs.112728
Chromosome Mapping:   22q11.22

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