PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CD46, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013380; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019289
Chromosome Location:   1:207925614-207930451question
Amplicon Length:   104

Gene Information

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I which protects the host cell from damage by complement. In addition the encoded protein can act as a receptor for the Edmonston strain of measles virus human herpesvirus-6 and type IV pili of pathogenic Neisseria. Finally the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq Jun 2010]

Gene Symbol:   CD46
Gene Name:   CD46 molecule, complement regulatory protein
Aliases:   AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10
RefSeq:   NC_000001.10 NG_009296.1 NT_167186.1
Ensembl:   ENSG00000117335
Entrez:   4179
UniGene:   Hs.510402
Chromosome Mapping:   1q32

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