PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TG, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013354; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019270
Chromosome Location:   8:134125775-134128951question
Amplicon Length:   142

Gene Information

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination and subsequent thyroxine biosynthesis in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis manifested as goiter and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq Nov 2009]

Gene Symbol:   TG
Gene Name:   thyroglobulin
Aliases:   AITD3, TGN
RefSeq:   NC_000008.10 NG_015832.1 NT_008046.16
Ensembl:   ENSG00000042832
Entrez:   7038
UniGene:   Hs.654591
Chromosome Mapping:   8q24

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