PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RAD50, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013265; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019208
Chromosome Location:   5:131923710-131924477question
Amplicon Length:   141

Gene Information

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50 a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein cooperating with its partners is important for DNA double-strand break repair cell cycle checkpoint activation telomere maintenance and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq Apr 2010]

Gene Symbol:   RAD50
Gene Name:   RAD50 homolog (S. cerevisiae)
Aliases:   NBSLD, RAD502, hRad50
RefSeq:   NC_000005.9 NG_021151.1 NT_034772.6
Ensembl:   ENSG00000113522
Entrez:   10111
UniGene:   Hs.633509
Chromosome Mapping:   5q31

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