PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PMEL, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013129; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019121
Chromosome Location:   12:56349905-56350791question
Amplicon Length:   128

Gene Information

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes which are the melanin-producing organelles in melanocytes and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq Jan 2011]

Gene Symbol:   PMEL
Gene Name:   premelanosome protein
Aliases:   D12S53E, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV, gp100
RefSeq:   NC_000012.11 NG_028086.1 NT_029419.12
Ensembl:   ENSG00000185664
Entrez:   6490
UniGene:   Hs.95972
Chromosome Mapping:   12q13-q14

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