PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TNNI1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013035; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019055
Chromosome Location:   1:201379465-201380537question
Amplicon Length:   122

Gene Information

Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI) along with troponin T (TnT) and troponin C (TnC) is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch TnI-skeletal-slow-twitch and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers respectively while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq Jul 2008]

Gene Symbol:   TNNI1
Gene Name:   troponin I type 1 (skeletal, slow)
Aliases:   DKFZp451O223, SSTNI, TNN1
RefSeq:   NC_000001.10 NG_016649.1 NT_004487.19
Ensembl:   ENSG00000159173
Entrez:   7135
UniGene:   Hs.320890
Chromosome Mapping:   1q31.3

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