PrimePCR™ ddPCR™ Expression EvaGreen® Assay: KPNA2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012953; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5019003
Chromosome Location:   17:66038405-66039065question
Amplicon Length:   80

Gene Information

The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae) which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq Jul 2008]

Gene Symbol:   KPNA2
Gene Name:   karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
Aliases:   IPOA1, QIP2, RCH1, SRP1alpha
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000182481
Entrez:   3838
UniGene:   Hs.594238
Chromosome Mapping:   17q24.2

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