PrimePCR™ ddPCR™ Expression EvaGreen® Assay: E2F4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012808; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018898
Chromosome Location:   16:67227375-67228652question
Amplicon Length:   140

Gene Information

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP) a transactivation domain enriched in acidic amino acids and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB p107 and p130 but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq Jul 2008]

Gene Symbol:   E2F4
Gene Name:   E2F transcription factor 4, p107/p130-binding
Aliases:   E2F-4
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000205250
Entrez:   1874
UniGene:   Hs.108371
Chromosome Mapping:   16q21-q22

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