PrimePCR™ ddPCR™ Expression EvaGreen® Assay: OGG1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012607; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018761
Chromosome Location:   3:9792054-9792686question
Amplicon Length:   82

Gene Information

This gene encodes the enzyme responsible for the excision of 8-oxoguanine a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups type 1 and type 2 depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described but the full-length nature for every variant has not been determined. [provided by RefSeq Aug 2008]

Gene Symbol:   OGG1
Gene Name:   8-oxoguanine DNA glycosylase
Aliases:   HMMH, HOGG1, MUTM, OGH1
RefSeq:   NC_000003.11 NT_022517.18 NG_012106.1
Ensembl:   ENSG00000114026
Entrez:   4968
UniGene:   Hs.380271
Chromosome Mapping:   3p26.2

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