PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PLAT, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012552; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018719
Chromosome Location:   8:42033605-42036498question
Amplicon Length:   119

Gene Information

This gene encodes tissue-type plasminogen activator a secreted serine protease which converts the proenzyme plasminogen to plasmin a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   PLAT
Gene Name:   plasminogen activator, tissue
Aliases:   DKFZp686I03148, T-PA, TPA
RefSeq:   NC_000008.10 NG_023264.1 NT_167187.1
Ensembl:   ENSG00000104368
Entrez:   5327
UniGene:   Hs.491582
Chromosome Mapping:   8p12

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