PrimePCR™ ddPCR™ Expression EvaGreen® Assay: APLP2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012534; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018706
Chromosome Location:   11:129998994-129999979question
Amplicon Length:   125

Gene Information

This gene encodes amyloid precursor- like protein 2 (APLP2) which is a member of the APP (amyloid precursor protein) family including APP APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin- copper- and zinc- binding domains at the N-terminus BPTI/Kunitz inhibitor and E2 domains in the middle region and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2011]

Gene Symbol:   APLP2
Gene Name:   amyloid beta (A4) precursor-like protein 2
Aliases:   APLP-2, APPH, APPL2, CDEBP
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000084234
Entrez:   334
UniGene:   Hs.370247
Chromosome Mapping:   11q23-q25,11q24

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