PrimePCR™ ddPCR™ Expression EvaGreen® Assay: WISP3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012412; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018618
Chromosome Location:   6:112389565-112390653question
Amplicon Length:   119

Gene Information

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain von Willebrand factor type C module thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia an autosomal recessive skeletal disorder indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   WISP3
Gene Name:   WNT1 inducible signaling pathway protein 3
Aliases:   CCN6, LIBC, MGC125987, MGC125988, MGC125989, PPAC, PPD
RefSeq:   NC_000006.11 NG_011748.1 NT_025741.15
Ensembl:   ENSG00000112761
Entrez:   8838
UniGene:   Hs.558428
Chromosome Mapping:   6q21

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