PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ACVR1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012283; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018529
Chromosome Location:   2:158637057-158656011question
Amplicon Length:   99

Gene Information

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins composed of a ligand-binding extracellular domain with cysteine-rich region a transmembrane domain and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq Jul 2008]

Gene Symbol:   ACVR1
Gene Name:   activin A receptor, type I
Aliases:   ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
RefSeq:   NC_000002.11 NG_008004.1 NT_005403.17
Ensembl:   ENSG00000115170
Entrez:   90
UniGene:   Hs.470316
Chromosome Mapping:   2q23-q24

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