PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ACTN4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012278; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018525
Chromosome Location:   19:39215184-39216475question
Amplicon Length:   104

Gene Information

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions where it is involved in binding actin to the membrane. In contrast skeletal cardiac and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle alpha actinin isoform which is concentrated in the cytoplasm and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq Jul 2008]

Gene Symbol:   ACTN4
Gene Name:   actinin, alpha 4
Aliases:   ACTININ-4, DKFZp686K23158, FSGS, FSGS1
RefSeq:   NC_000019.9 NG_007082.2 NT_011109.16
Ensembl:   ENSG00000130402
Entrez:   81
UniGene:   Hs.270291
Chromosome Mapping:   19q13

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