PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ARHGEF3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012274; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018522
Chromosome Location:   3:56785328-56787590question
Amplicon Length:   126

Gene Information

Rho-like GTPases are involved in a variety of cellular processes and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor which specifically activates two members of the Rho GTPase family: RHOA and RHOB both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD) indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   ARHGEF3
Gene Name:   Rho guanine nucleotide exchange factor (GEF) 3
Aliases:   DKFZp434F2429, FLJ98126, GEF3, MGC118905, STA3, XPLN
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000163947
Entrez:   50650
UniGene:   Hs.476402
Chromosome Mapping:   3p21-p13

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