PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PION, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012228; Intron-spanning

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018486
Chromosome Location:   7:76958672-76959676question
Amplicon Length:   128

Gene Information

Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311) a protease with numerous substrates. PION or GSAP selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF) (He et al. 2010 [PubMed 20811458]).[supplied by OMIM Nov 2010]

Gene Symbol:   PION
Gene Name:   pigeon homolog (Drosophila)
Aliases:   DKFZp667B242, GSAP, MGC126548
RefSeq:   NC_000007.13 NT_007933.15
Ensembl:   ENSG00000186088
Entrez:   54103
UniGene:   Hs.186649
Chromosome Mapping:   7q11.23

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