PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TP53I3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0011877; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018220
Chromosome Location:   2:24303844-24305789question
Amplicon Length:   63

Gene Information

The protein encoded by this gene is similar to oxidoreductases which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq May 2011]

Gene Symbol:   TP53I3
Gene Name:   tumor protein p53 inducible protein 3
Aliases:   PIG3
RefSeq:   NC_000002.11 NT_022184.15
Ensembl:   ENSG00000115129
Entrez:   9540
UniGene:   Hs.50649
Chromosome Mapping:   2p23.3

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