PrimePCR™ ddPCR™ Expression EvaGreen® Assay: VRK1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0011636; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5018032
Chromosome Location:   14:97321619-97322525question
Amplicon Length:   104

Gene Information

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells such as those in testis thymus fetal liver and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and in vitro to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene therefore may regulate cell proliferation. This protein also phosphorylates histone casein and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq Jul 2008]

Gene Symbol:   VRK1
Gene Name:   vaccinia related kinase 1
Aliases:   MGC117401, MGC138280, MGC142070, PCH1
RefSeq:   NC_000014.8 NG_016293.1 NT_026437.12
Ensembl:   ENSG00000100749
Entrez:   7443
UniGene:   Hs.422662
Chromosome Mapping:   14q32

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