PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TYMS, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0011569; Intron-spanning

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5017981
Chromosome Location:   18:670823-672869question
Amplicon Length:   96

Gene Information

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 510-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil 5-fluoro-2-prime-deoxyuridine and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq Jul 2008]

Gene Symbol:   TYMS
Gene Name:   thymidylate synthetase
Aliases:   HST422, MGC88736, TMS, TS
RefSeq:   NC_000018.9 NT_010859.14
Ensembl:   ENSG00000176890
Entrez:   7298
UniGene:   Hs.369762
Chromosome Mapping:   18p11.32

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